A Histoplasmosis (caused by the fungal pathogen Histoplasma capsulatum) is typically seen only in the Ohio and Mississippi river valleys, whereas Aspergillosis (caused by the fungal pathogen Aspergillus fumigatus) is widespread regardless of geographical location. Which of the following statements describes why this disparity with regards to disease distribution occurs? 1. Histoplasma capsulatum is an endemic fungus that prefers sols erwiched with bal guano, whereas Aspergillus furgatus is a ubiquitous soll langus.
2. Individuals are not as routinely vaccinated against Aspergillosis as compared to Histoplasmosis
3. Histoplasma capsulatum is an opportunistic fungal pathogen affecting immunocompromised individuals, whereas Aspergillus fumigatus is a true fungal pathogen affecting both healthy and immunocompromised individuals.
4. The arthropod vector that carries Histoplasma capsulatum is only found in the Ohio and Mississippi valley regions, whereas the arthropod vector that carries Aspergillus fumigatus is found in many geographical locations.

3. Histoplasma capsulatum is an opportunistic fungal pathogen that affects immunocompromised individuals, while Aspergillus fumigatus is a true fungal pathogen that affects both healthy and immunocompromised individuals.

Explanation:

Histoplasmosis is an oprtounista mycosis, that is to say that it increases in number in our organism occasionally generating infectious and non-protective pathology like the commensal flora.

Histoplasmosis respects American geographic limits and is because it lives in tropical and freshwater climates.

Histoplasmosis pathology is triggered if the person has a deficit in the immune response and if the risk of living or transiting the endemic area is corrected.

On the other hand, the aspergillus fungus is a fungus that enters the inhalation routes in a sporulated form and developed in the lungs, generating a high fatal risk, since it triggers inflammatory and necrotic symptoms in the lung, regardless of whether the person is immunodeficient or not. ... There were people who were shaved by this fungus and even selected hypersensitivity pictures, that is, the opposite of an immunodeficiency.

The Fungi of the Aspirgillus group do not discriminate against age, immune status, or other factors ... only inhalation of the spore is required to develop the pathological picture.

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