How could large molecules cross the cell mebrane

When molecules are too large or too charged to cross the plasma membrane by diffusion or osmosis, there are other methods to accomplish their transport into or out of the cell. For example, some proteins in the plasma membrane are known as protein channels and they form a way for large or charged molecules to pass through the membrane.

Explanation:

the answer that best describes the relative refractory period in the neuron is the resting membrane potential is restored, but concentrations of sodium and potassium are not restored to their original state.

the refractory period is the time during which another stimulus given to the neuron will not lead to a second potential. thus, because na+ channels are inactivated during this time, additional depolarizing stimuli do not lead to new action potentials.  

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the correct answer is: b. pantala flavescens, because these organisms would have a high level of genetic variation due to sexual reproduction.  

because involves two organisms (parents) whose genetic material combines, sexual reproduction leads to genetic variation in new generations of offspring. the offspring is an unique organism, with new genome, more protected with the higher ability to adapted. this process is fundamental to evolution.