Aldosterone exerts effects on principal cells of the kidney by causing:

A. increased levels of cAMP and increases in the total number of Na+ channels.
B. decreased levels of cAMP and decreases in the number of open K+ channels.
C. increased numbers of Na+/K+ pumps. decreased numbers of Na+/K+ pumps.

Option C.

Increased numbers of Na+/K+ pumps. Decreased numbers of Na+/K+ pumps.

Explanation:

Aldosterone is a steroid hormone produced by the zona glomerulosa of the adrenal cortex.

It activates sodium and potassium channels in the principal cells of distal tubules, collecting ducts. It acts as electrolytes in the distal tubules. It increase sodium reabsorption from the urine, sweat and duct.

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