With the proper stimuli, chemoreceptors and mechanoreceptors are depolarized. This is a result of:Sodium channels opening as a result of chemical or pressure-based stimuli. potassium channels opening

Sodium channels

Explanation:

Depolarization is a result of sodium channels opening as a result of chemical or pressure-based stimuli    

Depolarization starts when a threshold stimulus applied on a neuron via Na+ mechanically operated channels that trigger action potential Action potential is an efficient signaling process by which distantly located cells communicate to each other Depolarization of membrane potential is due to influx of Na+ via voltage gated Na+ channels Fast opening of voltage gated Na+ channel shifts membrane potential from -70mV to + 50mV at which voltage gated Na+ channels become inactive thus influx of Na+ abruptly stops        

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