A mutation takes place in a protein-coding gene that changes one codon resulting in a single amino acid replacement. Which type of replacement is least likely to result in a disruption of protein structure and function?
a) a hydrophobic amino acid to a hydrophilic amino acid
b) a polar amino acid to a hydrophobic amino acid
c) an acidic amino acid to a basic amino acid
d) a hydrophilic amino acid to a hydrophobic amino acid
e) a polar amino acid to a polar amino acid

The answer is A

Explanation:

you didn't give any options but heres what i can tell you: an inference is likely to change based on additional observations. the latter is something that you have seen or sensed using your sensory organs while the former is like a conclusion out from what you have observed.

before, trains worked using the steam engine. thus, it uses heat so it is crucial to apply heat balance. the steam engine absorbs energy during the stage of boiling water. so, this is the endothermic reaction. when the steam is used to work the piston, it has to release this energy through running the train. the excess energy is released as an exhaust to the chimney. this is the exothermic process because it releases energy to the surroundings.