Can someone Help me out please

What is the next step in the process after a substrate enters the active site of an enzyme

Which process takes place last in the human being which process takes place last in the development of a human being

How does the fossil record provide evidence that the modern whale evolved from the anthracotheres? a) the modern whale looks like their ancestor the anthracotheres. b) the modern whale has all of the same structures as their ancestor. c) there is not enough evidence to suggest the the modern whale evolved from the anthracotheres. d) the anthracotheres has a structure that is still present in the modern whale, but is no longer of use to the modern whale.