G DNA contains the template needed to copy itself, but it has no catalytic activity in cells. What catalyzes the formation of phosphodiester bonds between adjacent nucleotides in the DNA polymer being formed during DNA replication

DNA polymerase

Explanation:

The process in which DNA make its copies is called DNA replication.

It is true that DNA do not have any catalytic activity in the cells but there are several enzymes which participate in the process of DNA replication and performs different functions. DNA Polymerase is one of the key enzyme that participate in the process and catalyzes the formation of phosphodiester bonds between adjacent nucleotides in the DNA.

Arthur Kornberg in 1956 discovered DNA polymerase along with his colleague in Escherichia coli. DNA Polymerase catalyzes the addition of phosphodiester bonds with the help of formation of hydrogen bonds between the adjacent strands of DNA and build the backbone of DNA. Other functions of DNA polymerase involves  synthesis of DNA from the RNA primers , helps in the elongation of leading strand, and DNA sequencing.

Hence, DNA polymerase is catalyzes the formation of phosphodiester bonds between adjacent nucleotides in the DNA.

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