What are three different defects that could be responsible for malfunctioning lysosomes?

Three different defects that could be responsible for malfunctioning lysosomes are:

1. A defect in the mannose-6 phosphate receptor in the Golgi apparatus.

2 .A defect in a hydrolytic enzyme that breaks down polysaccharide.

3. A defect in the process of adding a mannose-6 phosphate signal to lysosome al hydrolases.

Explanation:

organelles involved in digestion and waste removal is the lysosome. Lysosomes are organelles that contain digestive enzymes. They digest excess or worn out organelles, food particles, and engulfed viruses or bacteria. People with malfunctioning lysosomes have disorders in which there are important enzymes missing (proteins that speed up reactions in the body). Without those enzymes, the lysosome isn't able to break down these substances.When lysosomes dysfuncton the body gets sick and lysosomal storage diseases occur.Some of the most common lysosomal storage disorders include: Gaucher disease,Glycogen storage disease II (Pompe disease), Neiman pick disease etc.

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