The same, unknown bacteria is isolated from 20 sick individuals. their samples were grown in culture and then placed in 10 healthy mice. those mice started to show signs of a heightened immune response. to determine if the bacteria is pathogenic, what is the next step by using koch’s postulates?

Ans.

Robert Koch gave four postulates to determine whether a given microbe or bacterium is causing a disease or not. These are:

-The bacterium must be found in all organisms with that disease.

-The bacterium can be isolated from the host (infected person) and grown in pure medium.

-The bacterium must cause disease when introduced into a healthy individual.

-The bacterium can be recover from the individual that was infected experimentally and it must be identified as original disease-causing agent.

Thus, according to the Koch postulates, 'the next step would be recovery of pathogenic bacterium from host that was infected experimentally and identification of bacterium to identify it as original disease causative bacterium.'

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