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Biology, 26.03.2020 22:41 loves2ballet

Many cases of severe combined immunodeficiency result from mutations in adenosine deaminase (an enzyme involved in nucleic acid turnover). Deficiency of this enzyme's activity leads to a 100-fold increase in dATP, yet also causes a deficiency in dNTPs required by lymphocytes for replication and proper immune function. Explain.

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