If you are performing site-directed mutagenesis to test predictions about which residues are essential for a protein’s function. Which of each pair of amino acid substitutions listed below would you expect to disrupt protein structure the most? And why? how do you go abouts knowing this?

a) Val replaced by Phe.

b) Lys replaced by Asp.

c) Gln replaced by Glu.

d) Pro replaced by His.

Explanation:

a) Although both amino acids are hydrophobic, Phe is a larger amino acid.

b) Since the Lys residue is positively charged and for that reason it would be more damaging to the protein.

c) The amide of the amino acid Asn would be the best option as a substitute for Gln than the amino acid Glu.

d) Due to the restricted geometry of the amino acid Pro, since the amino acid Gly does not have a side chain.

there are 35 white marbles

step-by-step explanation:

y- yellow marbles

4y + 5 = 45

subtract 5 from both sides

4y = 40

divide for from both sides

y = 10

plug in 10 to get 40 yellow marbles then subtract by 5 to get 35 marbles

thus there are only 10 yellow marbles

i think it’s c but i might be wrong. if i am let me know! have a good rest of your day as well!