Often,
substrate.
will bind within an enzyme's active site and produce a unique active site for the
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cofactors
apoenzymes

Explanation:

Enzymes are biochemicals which catalyze a biochemical reaction taking place in the body by reducing the activation energy barriers and changing the substrate molecules to products.  

The active sites of enzymes first binds to the substrate and forms an enzyme-substrate complex.

An enzyme can work actively only with the help of helper molecules called co-factors and co-enzymes.  

Co-factors are non-protein inorganic ions like iron, magnesium which helps the catalyze chemical reactions.  

Cofactors are bound tightly with the active sites of the enzymes and also contribute for the structural integrity and stability of the enzyme

answer and explanation;

volcanic rocks are igneous rocks which form from lava, molten rock which has been thrust out of a volcano onto the surface of a rocky body such as an asteroid, planet, or dwarf planet.  

plutonic rocks are igneous rocks which form from subterranean chambers of molten rock or magma. plutonic rocks make up the base of continental crust as well as oceanic crust. their slow rate of formation causes them to be coarse grained since there is plenty of time for large crystals to form before the magma solidifies into rock.

the textural difference is that plutonic rocks are more coarse grained than volcanic rocks. plutonic rocks are coarse grained while volcanic are fine grained ; glassey or fragmental. since fine and coarse are adjectives the decision as to whether a rock is fine or coarse grained is generally made on the bases of whether or not the individual crystals can be seen in most if the rock.