Identify the major problem that may occur
when tissues and organs donated by another
individual are used
explain why this problem may occur
explain why this problem will not occur if
tissues and organs produced by stem cells
from the patient are used

When tissues or organs are donated by another individual, the major problem arising is mismatch of DNA in the donor and the recipient leading to rejection or failure of the transplant.

Explanation:

When tissues or organs are donated by another individual, the major problem arising is mismatch of DNA in the donor and the recipient leading to rejection or failure of the transplant.

This is a major issue in allotransplantation where donor’s tissues with different DNA are transplanted.

Mismatch of DNA in the recipient can lead to apoptosis of tissues releasing the foreign DNA into the bloodstream which can cause very serious effects including death.

This problem can be best avoided by adapting stem cell therapy. Embryonic stem cells have the unique ability to differentiate into any organ system and replacing this will help to regenerate the worn out tissues.

Stem cells initiate organogenesis by growing or replicating the same type of tissues specific to the organ from primitive cells. Since all the cells of the body will have the same DNA, mismatch does not occur .

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