Thrombin catalyzes the activation of these molecules present in plasma. 2. : Makes up most of plasma protein. 3. : The major contributor to plasma osmotic pressure. 4. : Forms the structural framework of a blood clot.

1. when there is a cut, the surface area of the skin becomes rough which activates the Thrombin, that catalyzes the activation of fibrinogen present in plasma.

2. albumin contributes mostly of making plasma protein

3. albumin contributes the major portion to the osmotic pressure of plasma.

4. fibrinogen mainly forms the structural framework of a blood clot during blood coagulation.

that scientist would be robert hooke