Comparing intracellular to extracellular fluid, the intracellular fluid has a charge relative to the outside of a cell due to the presence of more in that solution.

Comparing intracellular to extracellular fluid, the intracellular fluid has a negative charge relative to the outside of a cell due to the presence of more anions in that solution.

intracellular fluid (ECF)contains more k⁺, Mg²⁺ than outside, hence bears a positive charge due to presence of more cations

extracellular fluid (ICF) contains more  Na⁻,Cl⁻ than inside,hence bears a negative charge due to presence of more anions.

Explanation:

sodium (Na⁻) and potassium (k⁺) plays a vital role in body fluid maintenance also known as body homeostasis and it also plays an important role in any cellular mechanism.  loss of Na⁻-k⁺  balance can leads some fatal conditions.

charged ECF and ICF helps to exchange ions and necessary things quickly during cellular function.

the glands which are associated with each description is given below: