Biology, 27.02.2020 18:17 tristan41

Identify mutations that have altered sexual development. How do you expect the following mutations to affect sexual development (more males/more females)?

a. A disabling mutation in the WNT4 coding sequence.
b. A disabling mutation in the DMRTI coding sequence.
c. A mutation in the FGF9 binding site on the WNT4 gene

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a. WNT4 protein is encoded by the WNT4 gene it is located in the chromosomes. WNT4 is responsible for the development of female features, while inhibiting the male development. Mutation of WNT4 gene will result in the Rokitansky-Kuster-Hauser syndrome.

b. Located in the 9th chromosome, DMRT1 (Doublesex and mad-3 related transcription factor 1) is the protein encoded by DMRT1 gene, it is responsible for the regulation of the gonadal sex distinction, thus sex (male) determination in multicellular eukaryotes. Mutation of this gene results in the deletion of 9p chromosome, causing abnormal testicular formation since the DMRT1 protein is found in the testicular cord and seritoli cells.

c. FGF9 promotes male sex development. Mutation causes an XY sex reversal.

Explanation:

Answer from: codyfore141

Option B

Explanation:

DMRTI gene is a protein responsible for regulating Sertoli cells and germ cells. It performs the function of testicle development in gonads during the sex determination period. Normal sexual development requires two copies of this gene.

Sertoli cells -> help in sperm-formation

Germ cells -> sex-cells

A disabling mutation in the DMRTI coding sequence causes a male-to-female sex reversal after sex determination. The deletion of this gene can cause male infertility as well.

Answer from: Quest

The scientific method is a series of steps followed by scientific investigators to answer specific questions about the natural world. it involves making observations, formulating a hypothesis, and conducting scientific experiments.the steps of the scientific method are •observation-the first step of the scientific method involves making an observation about something that interests you•question-once you've made your observation, you must formulate a question about what you have observed. •hypothesis-once you've made your observation, you must formulate a question about what you have observed. •experiment-once you've developed a hypothesis, you must design and conduct an experiment that will test it.•results-the results are where you report what happened in the experiment. •conclusion-the final step of the scientific method is developing a conclusion.i hope that this you : )

Answer from: Quest

d concave shape of wave rock

explanation:

the concave shape of wave rock is a very good evidence that supports the evolution of earth due to chemical weathering. if we talk about structure of wave rock, studies have estimated that it is around 2.7 billion years old. it also serves as the foundation of evidence that it was the place where australian continent began to form.

how the structure of wave rock was created?

studies suggest that structure of wave rock was created when the surrounded area was started to weather due to which deposition of material started on the part of land which now contains wave rock.

the structure of wave rock is considered to be one of the best-known landforms in australia. at the height of around 15 cm, there can be found flared slopes which formulate the margins of hyden rock. it is now assumed by geologists that wave rock was created by subsurface water-induced weathering and not by glaciers, waves or wind.

due to deposition of material over the period of long time, the wave rock became tougher and tougher due to weathering from surrounding terrain. this makes it a physical evidence that supports the evolution of earth due to chemical weathering.

hope it !

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Identify mutations that have altered sexual development. How do you expect the following mutations t...

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