What are the mechanisms of natural selection, and how do they lead to changes in
species over time?

Darwin's proposed mechanism for evolution is natural selection. Natural selection allows species to respond to their surroundings through time, or to become progressively excellently-suited. Natural selection is environmentally based and involves established heritable variation within a population.

They lead to changes in  species over time:

what subject is this

small, big, or no change could occur in the phenotype. it could cause something as simple as a cats ears to curl backwards or something as frighting as death. it could also occur in the protien-coding area and have an effect on that but no effect on the amino acids. what has to occur is a changing in the hox gene or the control gene.