Suppose that there are individuals in the population that have a mutation in an enzyme gene. The residue at position 50, which is normally aspartate, is substituted with alanine (D50A). The D50A mutation occurs at an area within the active site that is important for substrate binding, but not for enzyme catalysis.

(a) Predict how this would affect the KM, Vmax, and kcat for the enzyme. Insert your answer
(b) Compared to what you learned about inhibitors is this case, what type of inhibition would this mutation resemble?

a) Km = increase, Vmax and kcat = remain same

b) resembles competitive inhibition

Explanation:

Given Data:

a)

There would be increase in value of Km.

As higher substrate presence could overcome the presence of inhibitors so Vmax value would remain same.

The value of Kcat would also remain the same.

b)

The type of inhibition this mutation resembles is that of competitive inhibition.

yes it is weird but true

1: most common garden plants prefer loam — soils with a balance of different-sized mineral particles (approximately 40% sand, 40% silt, and 20% clay) with ample organic matter and pore space. however, some plants grow better in sandy soils, while others are well-adapted to clay soils.

2: available water capacity is the maximum amount of plant available water a soil can provide. it is an indicator of a soil's ability to retain water and make it sufficiently available for plant use. available water capacity is the water held in soil between its field capacity and permanent wilting point.

3: it is the same for all living things (plants and animals). it also includes very tiny organisms that our eyes cannot see. they are known as microorganisms, and include viruses, bacteria and fungi.