Which body of water did not serve a major trade route to constantinople

i think the miocene epoch spans the time from 23 million to 12 million years ago.

c

explanation:

the menstrual cycle – higher tier. negative feedback mechanisms affect the production of hormones in the menstrual cycle. oestrogen also stimulates the release of lh (luteinising hormone) from the pituitary gland, which in turn controls the production of progesterone.