Mutations in the exons of eukaryotic genes can result in changes in the translated protein. Nonexonic mutations, mutations in regions of a gene outside of the exons, can also alter the rate of transcription and the final protein. In which of the following situations would nonexonic mutations either affect expression of the gene or alter the structure of the final protein? Select all of the statements that apply. A.) An insertion at the 3' end of an intron causes the intron to remain attached to the exonB.) An insertion in a codon of the gene causes a transcriptional frameshift. C.) An insertion in the promoter region of the gene reduces RNA polymerase binding and inhibits gene transcription. D.) A mutation in a regulatory promoter reduces binding of an activator, resulting in a decrease in gene transcription. E.) Three base pairs are inserted into a region of an intron univnvoled in intron splicing.