Your ability to experience physical sensations is most likely to be disrupted by damage to your

thalamus

Explanation:

The thalamus is a gray nucleus located at the base of our brain that serves as an intersection point for multiple neuronal pathways. The clinical manifestations produced by thalamic lesions are very diverse, little systematizable and relatively little known.

In turn, these lesions respond to multiple causes, among which vascular predominates, although those of metabolic, neoplastic, inflammatory and infectious origin also stand out.

It integrates the somatic, visceral and visual information related to emotional sensations and subjective states, influences the activity of the motor cortex and serves as a relief to consciousness. So you can alter levels of awareness and alertness, emotional tone or recent memory, in addition to problems in sensitivity and movements.

We can talk about specific pathologies directly related to the thalamus lesion. Two of these injuries would be Korsakoff syndrome or Dejerine and Roussy syndrome. The first characterized by problems in anterograde memory, fabulations and hallucinations. The second due to severe pain, transient hemiparesis and hemiataxia.