Which of the following is true?

a. uncontrolled cell growth alone is sufficient for the development of cancers.
b. mutations that inactivate tumor suppressor genes are important in cancer.
c. cancer is a single disease with one underlying molecular cause.
d. cancer is a single disease resulting from a common set of mutations.

Imagine a self-reactive t cell that has not undergone clonal deletion in the thymus (that is to say, it has escaped central tolerance). if it encounters self antigen in the absence of an infection or inflammation, what will happen to this self-reactive t cell? (select two answers) (a) the t cell undergoes clonal expansion. (b) the t cell gains effector functions. (c) the t cell undergoes apoptosis. (d) the t cell becomes activated. (e) the t cell becomes anergic.