During vertebrate development, a sheet of epithelial tissue invaginates to form the neural tube, a structure that eventually forms the spinal cord and brain. mutations that interfere with the function of which proteins would be most likely to disrupt the epithelial sheet movement that drives this developmental process?

For the strategies below, decide whether they are best described as demand-side solutions or supply-side solutions to meeting human needs for fresh water. remember that a demand-side solution reduces demand for fresh water, whereas a supply-side solution increases the supply of fresh water. (a) damming a river to create a reservoir (b) desalinating seawater (c) a nation invading a neighboring country to access their rivers (d) raising water prices for consumers and businesses (e) providing tax breaks for companies that use less water (f) replacing inefficient irrigation with more-efficient drip irrigation to grow crops (g) requiring low-flow showerheads in all new homes