What follows are steps describing the series of reactions proposed to occur after the binding of a transcriptional activator to its response element on the dna. place them in the correct order.
(1) the chromatin remodeling complex binds to the core histones at the target region.
(2) the combined actions of the various molecular complexes increases promoter accessibility to the transcriptional machinery.
(3) the activator recruits a coactivator to a region of chromatin targeted for transcription.
(4) transcriptional machinery assembles at the site where transcription will be initiated.
(5) the coactivator acetylation the core histones of nearby nucleosomes.