Biologists have been able to produce mice that lack functioning genes for aquaporins. how would the urine of these mice compare to that of mice with normal aquaporins? a) lower volume and lower osmolarity b) higher volume and higher osmolarity c) higher volume and lower osmolarity d) lower volume and higher osmolarity

The answer is C.

Explanation:

Aquaporins are proteins that are located in cell membrane which transports water between intracellular and extracellular environment. Experimental evidence shows mice lacking aquaporins consumes ten times more fluid and secretes urine with lower osmolarity, which is called polyuria.

Source of experimental evidence: Ma T, Song Y, Yang B, Gillespie A, Carlson EJ, Epstein CJ, et al. Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proc Natl Acad Sci USA. 2000;97:4386–91.

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