Structure-based drug design strategies often devise competitive inhibitors that bind to certain enzyme active sites. for example saquinavir and indinavir are designed hiv protease inhibitors that bind to the aspartate protease enzyme of hiv, which is required for the virus to produce functional proteins for further hiv infection. which of the following statements are true about saquinavir and indinavir?

choose one or more:
a. very high local concentrations of proteins with phe-pro or tyr-pro peptide bonds would reduce the effectiveness of saquinavir and indinavir in limiting hiv's infectivity of new cells
b. the removal of the phenyi ring (six-membered carbon ring containing three double bonds and no attached (functional groups) on indinavir and saquinavir would likely affect their inhibitory activity
c. increasing concentrations of indinavir or saquinavir would result in a change in the a of the aspartate protease enzyme reaction
d. saquinavir and indinavir indinavir both have a component that mimics the natural phe-pro dipeptide substrate of aspartate protease

significant amounts of nitrogen oxides, carbon monoxide, and other pollution

explanation:

passenger vehicles are a major pollution contributor, producing significant amounts of nitrogen oxides, carbon monoxide, and other pollution. in 2013, transportation contributed more than half of the carbon monoxide and nitrogen oxides, and almost a quarter of the hydrocarbons emitted into our air.

the eggs of the insects should be the first thing collected at the scene.

false

it has to be understood that the sea water contains a huge amount of sodium and chlorine ions and if they enter the cell of the atlantic cod fish, the cell will shrivel and the fish will die. to avoid such a condition, the fish uses active transport for the purpose of removing the ions against the gradient.

explanation:

the atlantic cod is not a maritime osmoconformer. its native application of salts is less than that of the seawater it lives in. it is continually falling water from the gills to the ocean via osmosis.

countering that, the fish is going to be swallowing seawater. but since its internal collection of salts is lower than seawater, the fish will want to go free of excess salt, and since that's going upon a gradient, then active transport, requiring energy, must be used to pump out the salt. much marine fish use the organs to filter out the salt and these fish discharge very straight urine.

the "power" of a lens is its resolution power, or its ability to distinguish between to closely located points. with the low power lens, it is likely you will see the rough form of the hay and maybe some movement of dots around the hay. however, when observed with the high power lens, the detailed features of the hay become visible and the microbes being grown are more clearly visible.

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