Which of the following does not describe a mechanism for drug resistance?
group of answer choices

creation of new plasmids upon drug treatment

inactivation of the drug by hydrolysis

production of proteins that bind and sequester the drug

prevention of drug entry into the cell

changes in the structure of the drug's target

Creation of new plasmids upon drug treatment is not a mechanism of drug resistance.

Explanation:

Microbes can resist drug action by producing enzymes that deactivate drugs or destroy an antimicrobial by hydrolysis. Resistance mechanisms in some microbes inhibit drug action by preventing the entry of drugs into the cell target.

In this method the changes will be made in the lipid concentration of microbial cell membrane, porin channel selectivity and concentrations will be altered etc.

Since antimicrobial drugs are target specific alteration of the target structure of the drugs inhibition of β -lactam drug is an example of this kind of resistance. In the method of target mimicry proteins are produced that bind and sequester drugs and thus drugs won’t be able to bind to their targets.

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