Which of the following best describes the histones associated with eukaryotic dna? which of the following best describes the histones associated with eukaryotic dna? along a 10,000 base pair segment of dna, you expect to find twice as many molecules of histone protein h1, as histone protein h4. thousands of base pairs of dna often wrap around each nucleosome core particle more than a dozen times. the amino acid sequences of h4 vary extensively. within the nucleosome core particle, h1 is the most conserved and crucial histone protein. the five types of histone proteins are small, basic proteins with a positive charge that allows them to bind to dna.

The five types of histone proteins are small, basic proteins with a positive charge that allows them to bind to DNA.

Explanation:

Histones are the small eukaryotic proteins and have a molecular weight ranging from 11,000 to 21,000. These proteins are rich in basic amino acids arginine and lysine and therefore, are basic in nature. The R groups of both arginine and lysine are positively charged which in turn impart the overall positive charge to histone proteins.

The presence of phosphate groups makes the DNA strands negatively charged. The opposite charged of histone proteins and DNA strand facilitates the packing of DNA into nucleosomes. Five major classes of histones are present in all the eukaryotic cells. The amino acid sequences of H3 and H4 histones highly conserved while H1, H2A, and H2B histones exhibit less sequence conservation among various species of eukaryotes.

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