The researchers' experimental hypothesis was that changes in actin and myosin overlap would alter the number of myosin cross- bridges that could form within a sarcomere, and specifically that primer section key terms oa. increases in overlap favor more cross-bridges to form, increasing muscle force. muscle force. effect on muscle force. fiber) lengths. b. increases in overlap disrupt cross-bridge formation, reducing c. differences in overlap and cross-bridge formation have little d. overlap is minimal at intermediate sarcomere (and muscle e. none of the other answer options is correct