Histamine binds to the h1 g-protein-linked receptor to initiate the itchiness and airway constriction associated with an allergic response. if a mutation in the associated g-protein’s alpha subunit prevented the hydrolysis of gtp how would the allergic response change?
more severe allergic response compared to normal g-protein signaling.
less severe allergic response compared to normal g-protein signaling.
no allergic response.
no change compared to normal g-protein signaling.