How does an enzymes active site relate to its substrate

Which of the following describes a negative feedback loop? when the heart rate is too high, the body sends hormones that continually increase the heart rate higher. when a pregnant woman is in labor, the body sends hormones that increase the intensity of contractions, which then increases the secretion of the same hormones. when blood sugar is too low, the body sends hormones that raise blood sugar until it reaches a typical level and hormone secretion slows. when a person is jogging, the body sends hormones that continually decrease the rate of oxygen supply to the legs.

What organ is the first to receive nutrients that have been absorbed from the digestive tract?

What are the ingredients of oobleck?