Arrange the steps of a g-protein signal transduction in the order that they occur. a. the g protein dissociates from the receptor. b. the g protein activates an effector protein, leading to a cellular response. c. a signal molecule binds to the receptor activating it. d. the g protein is activated by the dissociation of gdp and binding of gtp. e. the receptor changes conformation and binds an inactive g protein.

c. A signal molecule binds to the receptor activating it.

d. The G Protein is activated by the dissociation of GDP and binding of GTP

a. The G protein dissociates from the receptor

b. The G protein activates an effector protein, leading to a cellular response.

e. The receptor changes conformation and binds an inactive G Protein.

Explanation:

G-protein receptors are plasma membrane receptors that are coupled with G-protein (guanine nucleotide-binding protein). After the signal binds for the receptor, receptor changes its conformation shape which results in the activation of G protein (GDP is changed with GTP). dissociated subunits of G protein can activate effector proteins (enzymes, ion channels etc) which leads to cell response. Hydrolysis of GTP to GDP inactivates the cascade.