Which of the following is/are true regarding the way aminoacyl-trna synthetases ensure the fidelity of translation? they can sense the improper fit of an amino acid and hydrolyze the intermediate prior to attachment to the trna. there is a short window of opportunity for the enzyme to hydrolyze the amino acid-trna bond before it is released for translation. the trna has a polynucleotide domain that is responsible for proofreading. aminoacyl-trna synthetases do not proofread.

Explanation:

An aminoacyl tRNA synthetase (aaRS) is a very important exhima during protein synthesis that is made through translation. This enzyme is an important factor not only for regulating the translation process, but also for the efficiency of a newly formed protein. This is because this enzyme is responsible for maintaining the fidelity of the genetic code during protein formation. This is done by detecting improper adjustment of an amino acid and hydrolyzing the intermediate prior to tRNA binding. furthermore, this enzyme may hydrolyze the amino acid-tRNA bond before being released for translation.

the sugar-phosphate backbone forms the structural framework of nucleic acids, including dna and rna. this backbone is composed of alternating sugar and phosphate groups, and defines directionality of the molecule.