The drug tacrolimus is used to prevent transplant rejection. predict the mechanisms of action of tacrolimus.

Tacrolimus drug has the purpose to reduce the activity of the recipient’s immune system. Tacrolimus’ mechanism includes inhibition of the production of interleukins. This is because interleukins (more precisely interleukin 2) promote the development and proliferation of T cells (T lymphocytes), which activate immune response.  

So, this drug inhibits both T cell signal transduction and IL-2 transcription.

well schools are being forced to embrace computers. unlike their "digital immigrant" teachers, these students are "digital natives", born into a world where technology is an integral part of everyday life. almost every student has access to a multitude of computers, laptops and tablet devices. it would be crazy to assume an assignment would  not be written on computer in this day and age.

don't delete this trying to

you must remain stopped until the stop signal is retracted and the red lights are turned off. approaching traffic in the opposite roadway of a divided highway shall not be required to stop, even if the school bus has the stop-arm extended and the alternately flashing warning signal lamps on.