What is the difference between normal and sickle hemoglobin at the dna, rna, and protein (amino acid) level?

Sickle hemoglobin is a genetic disease caused by a point mutation in one base. Thus, DNA difference is in nucleotide sequence  Changed DNA sequence is then transcribed into RNA, which now contains GUG instead of GAG. This changed RNA sequence is translated into misformed protein containing valine instead of glutamine.

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