Which of the following statements best predicts the effect of increasing the permeability of the mitochondrial membranes to large molecules?

The options missing from the question is given below:

The correct answer is  3 above.

ATP production reduces and ultimately drops due to the irregularities caused by the increased permeability of the mitochondrial membranes.

Also triggered by the increase in permeability are bioenergetic crises and a decrease in oxygen consumption rate.

Osmotic imbalance and changes in the ion homeostasis of the cell-matrix is the major causative factor for Mitochondrial swelling.

Learn more about Mitochondrial Membranes in the link below:

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